MMR
measles-mumps-rubella (vaccine)
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Autism Occurrence by MMR Vaccine Status Among US Children With Older Siblings With and Without Autism
An example of Healthy User Bias at work is the Jain et al 2015 MMR-autism study. In the Jain study children with pre-existing autism diagnosis are about 60% less likely to receive the MMR vaccine. Sick and already-vaccine-injured children don’t receive MMR, and therefore are concentrated in the control group.
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Vaccines are not associated with autism: an evidence-based meta-analysis of case-control and cohort studies
Healthy User Bias The OR (0.84) was almost significantly below 1 (p=0.07), which suggests that HUB is present in the MMR-autism studies. Notice that ORs for Hg/thimerosal studies are 1.00. Hg/thimerosal exposure occurs from the earliest vaccines (before neurodevelopmental problems are apparent), and this implies that HUB will be smaller in studies of Hg/thimerosal. From Taylor et al,…
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Measles-Containing Vaccines and Febrile Seizures in Children Age 4 to 6 Years
The word Autism does not appear in this article. Drs Klein and Baxter reports research support from Merck & Co, Novartis, GlaxoSmithKline, Pfizer, and Sanofi-Pasteur; Dr Jackson reports research support from Novartis Vaccines, Sanofi-Pasteur, and Pfizer; Dr Belongia receives reports research support from MedImmun
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Lack of association between measles-mumps-rubella vaccination and autism in children: a case-control study
This study shows an apparent protective effect of MMR vaccines against autism of 83%!
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Lack of Association between Measles Virus Vaccine and Autism with Enteropathy: A Case-Control Study
This study is intended to refute the Wakefield study mentioned above. However, it made one critical distinction; it didn’t recruit children with autism who regressed after MMR vaccination. That, combined with a very small sample size, renders the results nearly meaningless.
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Measles vaccination and antibody response in autism spectrum disorders
The requirement for the current presence of these symptoms, for 14 or more days continuously, shows a singular lack of understanding of the episodic, fluctuating, and alternating (e.g. diarrhea/constipation) symptom profile experienced by these children. In our experience, ASD children with histologic enterocolitis typically have 1 to 2 unformed stools per day that are very…
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MMR-vaccine and regression in autism spectrum disorders: negative results presented from Japan
Compared children vaccinated with a combination measles vaccine to children vaccinated with a single measles vaccine. Does not exonerate measles shot in autism causation.
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Pervasive developmental disorders in Montreal, Quebec, Canada: prevalence and links with immunizations
Used a statistical trick by using MMR uptake data from one city (Quebec City) and comparing it to autism rates in a different city (Montreal).
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No effect of MMR withdrawal on the incidence of autism: a total population study
Tthe recommended schedule for MMR vaccination was 12 months of age. The authors define regression as demonstrable loss of skills after 18 months of age. Therefore children who have developed normally for the first year of life, who then receive an MMR at 12 months of age and who subsequently regress over the course of…
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MMR vaccination and pervasive developmental disorders: a case-control study
study goes a step further in highlighting the inadequacy of study designs that fail to isolate the correct case-group